انتشارات / RCSTIM
تاریخ: 2018/12/30
توسط: Dr Reza Saber
منتشر شده در: Biosensors and Bioelectronics, 122, pp. 8-15
فایل های پیوست:
URL منتشر شده: https://www.sciencedirect.com/science/article/pii/S0956566318306511

Akbari Nakhjavani SKhalilzadeh BSamadi Pakchin PSaber RGhahremani MHOmidi Y

Abstract


An early on-time detection of breast cancer can effectively affect the outcome of the treatment. Here, we developed an ultrasensitive, simple and reliable immunosensor to detect the lowest alteration of CA 15-3, the standard biomarker of breast cancer patients. The proposed immunosensor was achieved by modification of gold electrode by streptavidin to immobilize the biotinylated anti-CA 15-3 monoclonal antibody (mAb). Bovine serum albumin was used to prevent nonspecific binding.

https://www.ncbi.nlm.nih.gov/pubmed/30236808