منتشر شده در: Biosensors and Bioelectronics, 122, pp. 8-15
Akbari Nakhjavani S, Khalilzadeh B, Samadi Pakchin P, Saber R, Ghahremani MH, Omidi Y
An early on-time detection of breast cancer can effectively affect the outcome of the treatment. Here, we developed an ultrasensitive, simple and reliable immunosensor to detect the lowest alteration of CA 15-3, the standard biomarker of breast cancer patients. The proposed immunosensor was achieved by modification of gold electrode by streptavidin to immobilize the biotinylated anti-CA 15-3 monoclonal antibody (mAb). Bovine serum albumin was used to prevent nonspecific binding.